TGF beta 1 Rabbit Polyclonal Antibody
Catalog# HA500496
TGF beta 1 Rabbit Polyclonal Antibody
-
WB
-
Human
-
unconjugated
製品概要
製品名
TGF beta 1 Rabbit Polyclonal Antibody
抗体のタイプ
Rabbit Polyclonal Antibody
免疫原
Recombinant protein within human TGF beta 1 aa 20-210.
交差反応性（対応種属）
Human
検証済みアプリケーション
WB
標的分子量
Predicted band size: 44 kDa
ポジティブコントロール
Raji cell lysate, Saos-2 cell lysate, 786-0 cell lysate, A549 cell lysate.
コンジュゲーション
unconjugated
RRID
製品の特徴
形態
Liquid
濃度
保存方法
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
保存バッファー
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
アイソタイプ
IgG
精製方法
Immunogen affinity purified.
推奨希釈倍率
-
WB
-
1:1,000
ターゲット
機能
Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
背景・参考文献
1. Robertson I.B., et al. Regulation of the bioavailability of TGF-beta and TGF-beta-related proteins. Cold Spring Harb. Perspect. Biol. 8:0-0(2016).
2. Miyazono K., et al. A role of the latent TGF-beta 1-binding protein in the assembly and secretion of TGF-beta 1. EMBO J. 10:1091-1101(1991) .
サブセルラー局在
Extracellular matrix, Secreted.
UNIPROT #
別名
Cartilage-inducing factor antibody
CED antibody
Differentiation inhibiting factor antibody
DPD1 antibody
LAP antibody
Latency-associated peptide antibody
Prepro transforming growth factor beta 1 antibody
TGF beta 1 antibody
TGF beta antibody
TGF beta 1 protein antibody
詳細を見る画像
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Western blot analysis of TGF beta 1 on different lysates with Rabbit anti-TGF beta 1 antibody (HA500496) at 1/1,000 dilution.
Lane 1: Raji cell lysate
Lane 2: Saos-2 cell lysate
Lane 3: 786-0 cell lysate
Lane 4: A549 cell lysate
Lysates/proteins at 20 µg/Lane.
Exposure time: 3 minutes; ECL: K1801
Blocking: 5% NFDM/TBST, 1 hour at room temperature
Primary antibody: HA500496, 1/1,000 in 5% NFDM/TBST, overnight at 4 ℃
Secondary antibody: Goat anti-Rabbit IgG-HRP (HA1001), 1/50,000 in 5% NFDM/TBST, 1 hour at room temperature
Predicted band size: 44 kDa
Observed band size: 50 kDa
文献・引用論文
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Chrysin inhibits hypertrophic scar formation through TGF-β/Smad signaling pathways
ジャーナル: Journal Of Molecular Histology
DOI: 10.1007/s10735-025-10576-3
IF: 2.2
アプリケーション: WB
交差反応性: Human
掲載日: 2025 Sept
-
The Kinesin Eg5 Inhibitor K858 Enhances Radiosensitivity in Esophageal Squamous Cell Carcinoma and Affects the Expression of Epithelial-mesenchymal Transition Related Markers: In vitro and In vivo Studies
ジャーナル: Anti-Cancer Agents In Medicinal Chemistry
DOI: 10.2174/0118715206373782250211104402
IF: 3
アプリケーション: WB
交差反応性: Human
掲載日: 2025 Feb
-
Dietary biotin facilitates collagen deposition and myofiber growth and development, improving muscle chewiness and hardness in grass carp (Ctenopharyngodon idella)
ジャーナル: Food Bioscience
DOI: 10.1016/j.fbio.2025.107461
IF: 5.9
アプリケーション: WB
交差反応性: Fish
掲載日: 2025 Aug
-
Hongjingtian alleviates arsenic-induced hepatocyte injury by inhibiting oxidative stress and endoplasmic reticulum stress
ジャーナル:
DOI: 10.1080/10286020.2025.2481290
IF:
アプリケーション: WB
交差反応性: Fish
掲載日: 2025 Apr
-
PEEP application during mechanical ventilation contributes to fibrosis in the diaphragm
ジャーナル: Respiratory Research
DOI:
IF: 7.162
アプリケーション: WB
交差反応性: Rabbit
掲載日: 2023 Feb
ご注意: 本製品はすべて「研究用試薬」です。人や動物の診断・治療目的、または臨床診断には使用できません。（FOR RESEARCH USE ONLY）
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