Human APP, C-His Tag (ECD) Protein

RMB: 900 特別割引 900

製品仕様

20μg

50μg

100μg

今すぐ注文，【现货】

問い合わせをクリック

お問い合わせ

メール: [email protected]

電話: 0571-88062880

代理店を調べる

Catalog# HA211180

Human APP, C-His Tag (ECD) Protein

Product Information

Product name

Human APP, C-His Tag (ECD) Protein

Catalog No.

HA211180

Predicted molecular mass

75.8 kD

Protein construction description

A DNA sequence encoding the human APP protein (P05067) (Leu 18-Met 671) was expressed with a His tag at the C-terminus.

Accession

P05067

Protein construction

APP (18-671) His

Source

HEK293

Bio Activity

Testing in progress.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.