Iba1 Rabbit Polyclonal Antibody
Catalog# ER1802-20
Iba1 Rabbit Polyclonal Antibody
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IHC-P
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Human
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Mouse
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unconjugated
製品概要
製品名
Iba1 Rabbit Polyclonal Antibody
抗体のタイプ
Rabbit Polyclonal Antibody
免疫原
Synthetic peptide within C-terminal human Iba1.
交差反応性（対応種属）
Human, Mouse
検証済みアプリケーション
IHC-P
分子量
17/10/15 kDa
ポジティブコントロール
Human tonsil tissue, human spleen tissue, mouse spleen tissue.
コンジュゲーション
unconjugated
RRID
製品の特徴
形態
Liquid
濃度
保存方法
Shipped at 4℃. Store at +4℃ short term (1-2 weeks). It is recommended to aliquot into single-use upon delivery. Store at -20℃ long term.
保存バッファー
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
アイソタイプ
IgG
精製方法
Immunogen affinity purified.
推奨希釈倍率
-
IHC-P
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1:50-1:200
ターゲット
機能
Ionized calcium-binding adapter molecule 1 (Iba1), also known as allograft inflammatory factor-1 (AIF-1), is a 147 amino acid cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. Iba1, containing two EF domains, is induced by cytokines and interferons. In an unstimulated state, Iba1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding Iba1 maps to chromosome 6p21.33 and resides in the tumor necrosis factor (TNF) cluster of genes located in the region represented by the human major histocompatibility complex (MHC).
背景・参考文献
暂无
組織特異性
Detected in T-lymphocytes and peripheral blood mononuclear cells.
翻訳後修飾（PTM）
Phosphorylated on serine residues.
サブセルラー局在
Plasma membrane. Cytoskeleton.
別名
AIF 1 antibody
AIF-1 antibody
Aif1 antibody
AIF1 protein antibody
AIF1_HUMAN antibody
Allograft inflammatory factor 1 antibody
Allograft inflammatory factor 1 splice variant G antibody
allograft inflammatory factor-1 splice variant Hara-1 antibody
balloon angioplasty responsive transcription antibody
BART 1 antibody
詳細を見る画像
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Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Iba1 antibody. Counter stained with hematoxylin.
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Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-Iba1 antibody. Counter stained with hematoxylin.
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Immunohistochemical analysis of paraffin-embedded mouse spleen tissue using anti-Iba1 antibody. Counter stained with hematoxylin.
ご注意: 本製品はすべて「研究用試薬」です。人や動物の診断・治療目的、または臨床診断には使用できません。（FOR RESEARCH USE ONLY）
文献・引用論文
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Effect of Puerarin on Chronic Alcoholic Encephalopathy by Modulating the “Microbiota-Gut-Brain Axis” Lipopolysaccharides/Toll-Like Receptors 4/Nuclear Factor Kappa-B Inflammatory Pathway
ジャーナル: Phytotherapy Research
DOI: 10.1002/ptr.70197
IF: 6.3
アプリケーション: IHC
交差反応性: Mouse
掲載日: 2026 Jan
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Fluorescence spectra of cell markers in the spinal cord for a murine model of amyotrophic lateral sclerosis with heat shock protein overexpression
ジャーナル: Laser Physics Letters
DOI: 10.1088/1612-202X/ada7d8
IF: 1.4
アプリケーション: IF-tissue
交差反応性: Mouse
掲載日: 2025 Jun
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Porphyromonas gingivalis Induces Disturbance of Kynurenine Metabolism Through the Gut-Brain Axis: Implications for Alzheimer’s Disease
ジャーナル: JOURNAL OF DENTAL RESEARCH
DOI: 10.1177/00220345241303141
IF: 5.9
アプリケーション: IHC
交差反応性: Mouse
掲載日: 2025 Feb
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Quantitative Immunofluorescence Mapping of HSP70’s Neuroprotective Effects in FUS-ALS Mouse Models
ジャーナル: Applied Sciences-Basel
DOI: 10.3390/app142411614
IF: 2.5
アプリケーション: IF-tissue
交差反応性: Mouse
掲載日: 2024 Dec
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