CD31 Recombinant Antibody [7-A1-R] - Rat IgG1 (Chimeric)

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Catalog# HA601522

CD31 Recombinant Antibody [7-A1-R] - Rat IgG1 (Chimeric)

Application

IHC-P

Reactivity

Human

BSA and Azide free

HA610349
不含抗保成分

Conjugation

unconjugated

This product has been cited in peer reviewed publications, see list HERE

製品概要

製品名

CD31 Recombinant Antibody [7-A1-R] - Rat IgG1 (Chimeric)

抗体のタイプ

Recombinant Chimeric Antibody

免疫原

Synthetic peptide (KLH-coupled) within C-terminal residues of human CD31.

交差反応性（対応種属）

Human

検証済みアプリケーション

IHC-P

分子量

Predicted band size: 83 kDa

ポジティブコントロール

Human appendix tissue, human gastric cancer tissue, human kidney tissue, human liver tissue.

コンジュゲーション

unconjugated

クローン番号

7-A1-R

Reactivity Data

Tested

検証済（社内検証通過） Published

文献報告済（社内未検証、文献サポートあり） Predicted

反応性予測（高い相同性に基づく） Not recommended

非推奨（社内検証未通過）

	IHC-P
Human

製品の特徴

形態

Liquid

濃度

ロット濃度照会

保存方法

Shipped at 4℃. Store at +4℃ short term (1-2 weeks). Store at -20℃ long term.

保存バッファー

1*PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.

精製方法

Protein A affinity purified.

推奨希釈倍率

IHC-P
1:1,000

ターゲット

機能

Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors including neuroblastomas, rhabdomyosarcomas, Wilms’ tumors, Ewing’s sarcomas and some primitive myeloid malignancies. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily. PECAM-1 (platelet/endothelial cell adhesion molecule-1), also referred to as CD31, is a glycoprotein expressed on the cell surfaces of monocytes, neutrophils, platelets and a subpopulation of T cells. VCAM-1 (vascular cell adhesion molecule-1) was first identified as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) and lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM)-like protein and is deleted in 66% of patients with Kallmann’s syndrome, anosmia with secondary hypogonadism.

背景・参考文献

1. Doi H et al. Potency of umbilical cord blood- and Wharton\'s jelly-derived mesenchymal stem cells for scarless wound healing. Sci Rep 6:18844 (2016).

2. Yang Y et al. The Increased Expression of Connexin and VEGF in Mouse Ovarian Tissue Vitrification by Follicle Stimulating Hormone. Biomed Res Int 2015:397264 (2015).

サブセルラー局在

Cell junction. Cell membrane. Membrane.

UNIPROT #

SwissProt: P16284 Human

別名

Adhesion molecule antibody

CD31 antibody

CD31 antigen antibody

CD31 EndoCAM antibody

EndoCAM antibody

FLJ34100 antibody

FLJ58394 antibody

GPIIA antibody

GPIIA' antibody

PECA1 antibody

詳細を見る

画像

Immunohistochemical analysis of paraffin-embedded human appendix tissue with Rat anti-CD31 antibody (HA601522) at 1/1,000 dilution.

The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH₂O and PBS, and then probed with the primary antibody (HA601522) at 1/1,000 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
Immunohistochemical analysis of paraffin-embedded human appendix tissue with Rat anti-CD31 antibody (HA601522) at 1/1,000 dilution.

The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH₂O and PBS, and then probed with the primary antibody (HA601522) at 1/1,000 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
Immunohistochemical analysis of paraffin-embedded human gastric cancer tissue with Rat anti-CD31 antibody (HA601522) at 1/1,000 dilution.

The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH₂O and PBS, and then probed with the primary antibody (HA601522) at 1/1,000 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
Immunohistochemical analysis of paraffin-embedded human kidney tissue with Rat anti-CD31 antibody (HA601522) at 1/1,000 dilution.

The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH₂O and PBS, and then probed with the primary antibody (HA601522) at 1/1,000 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
Immunohistochemical analysis of paraffin-embedded human liver tissue with Rat anti-CD31 antibody (HA601522) at 1/1,000 dilution.

The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ddH₂O and PBS, and then probed with the primary antibody (HA601522) at 1/1,000 dilution for 1 hour at room temperature. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

ご注意: 本製品はすべて「研究用試薬」です。人や動物の診断・治療目的、または臨床診断には使用できません。（FOR RESEARCH USE ONLY）

文献・引用論文

アプリケーションで絞り込む

種属で絞り込む

Selective targeting of endothelial and perivascular angiocrine ROCK2 treats liver fibrosis
- ジャーナル: Cell
- DOI: 10.1016/j.cell.2026.02.001
- IF: 42.5
- アプリケーション: IHC-P
- 交差反応性: Human
- 掲載日: 2026 Mar

CD31 Recombinant Antibody [7-A1-R] - Rat IgG1 (Chimeric)

お問い合わせ

製品概要

製品名

抗体のタイプ

免疫原

交差反応性（対応種属）

検証済みアプリケーション

分子量

ポジティブコントロール

コンジュゲーション

クローン番号

Reactivity Data

製品の特徴

形態

濃度

保存方法

保存バッファー

精製方法

推奨希釈倍率

ターゲット

機能

背景・参考文献

サブセルラー局在

UNIPROT #

別名

画像

文献・引用論文

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CD31 Recombinant Rabbit Monoclonal Antibody [SU03-59] - BSA and Azide free

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Reactivity: Human

Conjugate: unconjugated