Human FGF-8b, Tag Free Protein

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20μg

50μg

100μg

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Catalog# HA211414

Human FGF-8b, Tag Free Protein

Product Information

Product name

Human FGF-8b, Tag Free Protein

Catalog No.

HA211414

Predicted molecular mass

24.4 kD

Protein construction description

A DNA sequence encoding the human FGF-8b protein (P55075-3) (Gln 23-Arg 215) was expressed with tag Free.

Accession

P55075-3

Protein construction

FGF-8b (23-215)

Source

HEK293

Bio Activity

Measured in a cell proliferation assay using NIH/3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 10-60 ng/mL.

Purity

>95% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU per μg by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.

Species

Human

Background

Fibroblast growth factor 8 (FGF-8) is a protein that in humans is encoded by the FGF8 gene. The protein encoded by this gene belongs to the fibroblast growth factor (FGF) family. FGF proteins are multifunctional signaling molecules with broad mitogenic and cell survival activity, playing critical roles in embryonic development, cell proliferation, morphogenesis, tissue repair, and tumor progression. FGF8 signals primarily through fibroblast growth factor receptor 1 (FGFR1) to trigger downstream pathways involved in neural and limb development.

Usage guide

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped with blue ice. Bulk packages of recombinant proteins are provided as frozen liquid which are shipped with dry ice.

Storage

Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.