Percp-Cy5.5 Conjugated Human CD3 Recombinant Mouse Monoclonal Antibody [PSH04-92]
Catalog# HA601548F
Percp-Cy5.5 Conjugated Human CD3 Recombinant Mouse Monoclonal Antibody [PSH04-92]
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FC
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Human
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Percp-Cy5.5
概要
製品名
Percp-Cy5.5 Conjugated Human CD3 Recombinant Mouse Monoclonal Antibody [PSH04-92]
抗体の種類
Recombinant Mouse Monoclonal Antibody
免疫原
Recombinant protein within Human CD3 23-126.
種属反応性
Human
検証された応用例
FC
分子量
Predicted band size: 23 kDa
結合
Percp-Cy5.5
クローン番号
PSH04-92
製品の特徴
形態
Liquid
保存方法
Store at 2℃ to 8℃. Avoid repeated freeze / thaw cycles.
保存用バッファー
Supplied in phosphate-buffered solution, pH 7.2, containing 0.2% ProClean 950 and BSA.
アイソタイプ
IgG1
精製方法
Protein A affinity purified.
応用希釈度
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FC
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5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
論文における応用例
| FC | 確認する 1 以下の論文 |
論文における種属
| Mouse | 確認する 1 以下の論文 |
ターゲット
機能
CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with the T-cell receptor (TCR) and the CD3-zeta (ζ-chain) to generate an activation signal in T lymphocytes. The TCR, CD3-zeta, and the other CD3 molecules together constitute the TCR complex.
背景文献
1. LeFevre JD et al. Anti-CD3 monoclonal antibodies for the prevention and treatment of type 1 diabetes: A literature review. Am J Health Syst Pharm. 2022 Nov
2. Chen Y et al. Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility. Mol Cell. 2022 Apr
亜細胞局在
Cell membrane.
UNIPROT #
別名
CD3 epsilon antibody
CD3e antibody
CD3e antigen antibody
CD3e antigen epsilon polypeptide (TiT3 complex) antibody
CD3E antigen epsilon polypeptide antibody
CD3E antigen, epsilon subunit antibody
CD3e molecule epsilon antibody
CD3e molecule, epsilon (CD3 TCR complex) antibody
CD3e molecule, epsilon (CD3-TCR complex) antibody
CD3E_HUMAN antibody
展開画像
ご注意ください: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
論文での実績
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Near-infrared activatable engineered bacteria for synergistic cancer photo-immunotherapy
Author: Qinglian Hu, Ying He, Zhuoting Lu, Xikai Zhang, Jie Liu, Yuanxiang Jin
PMID: NOPMID25112803
Journal: Chemical Engineering Journal
アプリケーション: FC
交差性: Mouse
掲載日: 2025 Oct
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Citation
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Human CD3 Recombinant Mouse Monoclonal Antibody [PSH04-92]
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PE Conjugated Human CD3 Recombinant Mouse Monoclonal Antibody [PSH04-92]
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