QKI-6 Recombinant Antibody [PSH10-23] - Guinea pig IgG2 (Chimeric) - BSA and Azide free
Catalog# HA610332
QKI-6 Recombinant Antibody [PSH10-23] - Guinea pig IgG2 (Chimeric) - BSA and Azide free
-
IHC-Fr
-
WB
-
Mouse
-
Rat
-
HA601502
含抗保成分
-
unconjugated
製品概要
製品名
QKI-6 Recombinant Antibody [PSH10-23] - Guinea pig IgG2 (Chimeric) - BSA and Azide free
抗体のタイプ
Recombinant Chimeric Antibody
免疫原
Synthetic peptide within human QKI-6 aa 281-319 / 319.
交差反応性（対応種属）
Mouse, Rat
検証済みアプリケーション
IHC-Fr, WB
標的分子量
Predicted band size: 35 kDa
ポジティブコントロール
Mouse brain tissue lysate, Rat brain tissue lysate.
コンジュゲーション
unconjugated
クローン番号
PSH10-23
製品の特徴
形態
Liquid
濃度
保存方法
Store at 2-8℃. Avoid freeze.
保存バッファー
1*PBS (pH7.4).
精製方法
Protein A affinity purified.
推奨希釈倍率
ターゲット
機能
Quaking homolog, KH domain RNA binding (mouse), also known as QKI, is a protein which in humans is encoded by the QKI gene. QKI belongs to a family of RNA-binding proteins called STAR proteins for Signal Transduction and Activation of RNA. They have an HNRNPK homology (KH) domain embedded in a 200-amino acid region called the GSG domain. Other members of this family include SAM68 (KHDRBS1) and SF1. Two more new members are KHDRBS3 and KHDRBS2. The QKI gene is implicated as being important in schizophrenia, and QKI controls translation of many oligodendrocyte-related genes.
背景・参考文献
1. Zhao Z et al. QKI shuttles internal m(7)G-modified transcripts into stress granules and modulates mRNA metabolism. Cell. 2023 Jul
2. Suh YY et al. MYB/MYBL1::QKI fusion-positive diffuse glioma. J Neuropathol Exp Neurol. 2023 Feb
サブセルラー局在
Cytoplasm, cytosol, Nucleus.
UNIPROT #
別名
DKFZp586I0923 antibody
HKQ antibody
Homolog of mouse quaking QKI KH domain RNA binding protein antibody
Hqk antibody
HQK1 antibody
HqkI antibody
OTTHUMP00000017581 antibody
OTTHUMP00000017582 antibody
OTTHUMP00000017583 antibody
Protein quaking antibody
詳細を見る画像
-
This data was developed using HA601502, the same antibody clone in a different buffer formulation.
Application: IHC-Fr
Species: Mouse
Site: cerebellum
Sample: Frozen section
Antibody concentration: 1/200
Antigen retrieval: Not required -
☑ Relative expression (RE)
This data was developed using HA601502, the same antibody clone in a different buffer formulation.
Western blot analysis of QKI-6 on different lysates with Guinea pig anti-QKI-6 antibody (HA601502) at 1/5,000 dilution.
Lane 1: Mouse brain tissue lysate
Lane 2: Mouse kidney tissue lysate (negative)
Lane 3: Rat brain tissue lysate
Lysates/proteins at 20 µg/Lane.
Predicted band size: 35 kDa
Observed band size: 35 kDa
Exposure time: 59 seconds; ECL: K1801;
4-20% SDS-PAGE gel.
Proteins were transferred to a PVDF membrane and blocked with 5% NFDM/TBST for 1 hour at room temperature. The primary antibody (HA601502) at 1/5,000 dilution was used in primary antibody dilution (K1803) at 4℃ overnight. Rabbit anti-Guinea pig IgG H&L - HRP Secondary Antibody (HA1021) at 1/50,000 dilution was used for 1 hour at room temperature.
ご注意: 本製品はすべて「研究用試薬」です。人や動物の診断・治療目的、または臨床診断には使用できません。（FOR RESEARCH USE ONLY）